RYCO AI
RYCO
Intraoperative · Robotic Assisted Bronchoscopy · EBUS-TBNA

RYCO AI

The AI Cytologist in Your Bronchoscopy Suite

Rapid Reads. In-Lesion Clarity.

AI-powered intraoperative cytology evaluation for robotic assisted bronchoscopy and EBUS-TBNA. Instant specimen adequacy confirmation — without a cytopathologist in the room.

How RYCO AI Works

Three steps. Seconds to verdict. No cytopathologist required.

01

Prepare Slide

Rapid smear prep with Diff-Quik stain (~1 min). Standard ROSE preparation.

02

Scan Slide

Upload from any digital microscope or use Live Microscope Mode for real-time capture.

03

Read Verdict

RYCO AI identifies cell types and delivers two simultaneous verdicts: location (IN LESION / NOT IN LESION) and specimen adequacy (Adequate / Inadequate).

Dual Procedure Modes

Robotic Assisted Bronchoscopy (IN LESION) and EBUS-TBNA (IN NODE) with separate AI logic for each.

Live Microscope Mode — Primary

Connect a USB microscope camera and RYCO reads directly from the live feed. No file export. Reads the slide as you look through the scope.

14+ Cell Types

Bronchial epithelium, alveolar macrophages, lymphocytes, atypical cells, malignant patterns and more.

Seconds to Result

Optimized for OR speed. RYCO reads the slide in 15–20 seconds. Total time from stained slide to verdict: under 60 seconds..

No PHI Collected

De-identified slide images only. No patient identifiers stored or transmitted.

Multi-Hospital Access

Institutional login system with per-hospital data isolation and admin dashboard.

Competitive Positioning

What Makes RYCO AI Different

Not “better AI” — a fundamentally different approach to intraoperative cytology.

01

Purpose-Built for One Clinical Question

RYCO AI does one thing: “Is this specimen adequate, and am I in the right location?” That narrow focus makes it faster and more actionable than tools that try to diagnose, classify, and stage.

02

It Knows the Procedure Context

Two separate modes — Robotic Assisted Bronchoscopy and EBUS-TBNA — each with its own adequacy criteria. A generic AI doesn’t know the difference. RYCO AI does.

03

Designed for the OR, Not the Lab

Other cytology AI tools process scanned slides after the procedure. RYCO AI is built for real-time intraoperative use: live camera feed, verdict in 15–20 seconds on any laptop or tablet.

04

It Speaks the Language of the OR

RYCO AI doesn’t return a pathology report. It says: “You’re in the lesion” or “You’re not there yet — reposition.” Direct, immediate, actionable.

The Real Differentiator

There is no other tool on the market that does what RYCO AI does.

Intraoperative, real-time, dual-mode cytology adequacy confirmation for robotic assisted bronchoscopy and EBUS-TBNA — accessible from any device, without a cytopathologist in the room. The competition is not another AI tool. The competition is having a cytotech in the room — which most programs cannot afford, cannot schedule, or simply do not have. RYCO AI replaces that gap entirely.

Ready to bring RYCO AI to your bronchoscopy program?

We are currently accepting a limited number of institutional pilot partners. Contact us to discuss an arrangement tailored to your program.

Not Generic AI

RYCO AI vs. Generic AI

Anyone can upload a slide to ChatGPT and get a paragraph. That's a parlor trick. RYCO AI is a trained pulmonary cytologist that happens to run on a computer.

Generic AI (ChatGPT, etc.)

Returns a paragraph — not a clinical verdict

No procedure context — doesn't know RAB vs. EBUS

No structured output — confidence scores, cell types, flags

No adequacy criteria — doesn't know what 'adequate for ROSE' means

Uploads to external servers — HIPAA risk

No history, no QI tracking, no case log

Built for everything — specialized for nothing

RYCO AI — Pulmonary Specialist

Returns IN LESION / NOT IN LESION — one clear verdict

Separate AI logic for RAB and EBUS-TBNA procedures

14+ cell types identified with confidence scores and atypical flags

Trained on ROSE adequacy criteria for pulmonary cytology

De-identified processing — no PHI, no HIPAA risk

Full QI case log, history, analytics, CSV export

Built for one thing: the bronchoscopy suite

RYCO AI is not a general AI that reads slides. It is a specialized intraoperative pulmonary cytologist — trained on pulmonary cytology, built for the bronchoscopy suite, and purpose-designed for the one question that matters in the room: "Is this specimen adequate?"

Peer-Reviewed Evidence · 2024–2026

The Science Is Clear — ROSE Works

The barrier to intraoperative cytology isn’t clinical efficacy — it’s access. Current peer-reviewed evidence confirms ROSE significantly improves specimen adequacy and diagnostic yield in bronchoscopic procedures.

93.9%

Concordance with final pathology in robotic bronchoscopy

Ali et al., J Thoracic Disease, 2026

95.7%

Accuracy distinguishing malignant from benign (peripheral lesions)

Yan & Jin et al., Frontiers in Oncology, 2025

100%

EBUS-TBNA adequacy rate with ROSE (specificity 100%)

Szűcs et al., Pathology & Oncology Research, 2026

“The presence of a cytopathologist at the time of sampling has been shown to improve diagnostic yield by assessing adequacy. However, due to increasing workload, this is rarely feasible in routine practice.”

— Szűcs et al., Pathology & Oncology Research, 2026

Current Supporting Studies

Diagnostic accuracy of ROSE during robotic bronchoscopy

2026

Ali MS et al. · Journal of Thoracic Disease

93.9% concordance with final pathology; 75% overall diagnostic yield with ROSE in robotic bronchoscopy

Diagnostic accuracy of ROSE in subtyping lung cancer via bronchoscopic biopsy

2025

Yan S, Jin F et al. · Frontiers in Oncology

93.92% overall concordance (κ = 0.87, near-perfect agreement); 95.66% accuracy for peripheral lesions

Sample adequacy in bronchoscopic ROSE: laboratory specialist vs. pathologist

2026

Szűcs G et al. · Pathology & Oncology Research

91.3% sensitivity, 100% specificity for adequacy; 100% adequacy rate with EBUS-TBNA

Cost-effectiveness of ROSE during navigational bronchoscopy

2024

Dahlberg GJ et al. · CHEST Pulmonary

ROSE increases diagnostic yield during navigational bronchoscopy; availability limited by cost and logistical constraints

RYCO AI brings the clinical benefit of ROSE to every bronchoscopy suite — without requiring a cytopathologist in the room. Learn more about the pilot program →